Captopril
Ibisobanuro
Captopril (SQ-14534) ninzitizi ikomeye, irwanya inzitizi ya angiotensin ihindura (ACE).
Muri Vitro
Captopril (SQ-14534) byagaragaye ko ifite uburwayi n’impfu zisa n’iza diuretique na beta-blokers ku barwayi ba hypertension.Captopril (SQ-14534) byagaragaye ko idindiza iterambere rya nepropatique ya diabete, kandi enalapril na lisinopril birinda indwara ya nepropatique kubarwayi ba Normoalbuminuric barwaye diyabete [1].Ikigereranyo cya equimolar ya cis na trans leta ya Captopril (SQ-14534) ibaho mugisubizo kandi ko enzyme ihitamo gusa trans transit ya inhibitor yerekana ubwubatsi hamwe na stereoelectronic yuzuzanya hamwe na substrate ihuza ibiti byayo [2].
MCE ntabwo yemeje ubwigenge ubu buryo.Nibisobanuro gusa.
Ikigeragezo cya Clinical
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Ububiko
Ifu | -20 ° C. | Imyaka 3 |
4 ° C. | Imyaka 2 | |
Mubishobora | -80 ° C. | Amezi 6 |
-20 ° C. | Ukwezi |
Imiterere yimiti
Icyifuzo18Imishinga yo gusuzuma ireme ryemejwe4, na6imishinga iremezwa.
Sisitemu mpuzamahanga yo gucunga neza ubuziranenge yashyizeho urufatiro rukomeye rwo kugurisha.
Igenzura ryiza rinyura mubuzima bwose bwibicuruzwa kugirango hamenyekane ingaruka nziza nubuvuzi.
Itsinda ryumwuga ushinzwe kugenzura ibikorwa byujuje ubuziranenge mugihe cyo gusaba no kwiyandikisha.