Crisaborole
Crisaborole ni umwe mubagize itsinda rya benzoxaboroles ni 5-hydroxy-1,3-dihydro-2,1-benzoxaborole irimo fenolikehydrogenyasimbuwe nitsinda rya 4-cyanophenyl. Foshodiesterase 4 inhibitor ikoreshwa mukuvura dermatite ya atopic yoroheje kandi yoroheje mubana ndetse nabakuze. Ifite uruhare nka fosiforiesterase IV inhibitor, anantipsoriaticn'umuti utari steroidal anti-inflammatory. Ni benzoxaborole, ether ya aromatic na nitrile.
Crisaborole nigitabooxaborolebyemejwe na FDA ku ya 14 Ukuboza 2016 nka Eucrisa, uburyo bwo kuvura indwara ya dermatite yoroheje cyangwa yoroheje. Iyi miti itari steroidal ifite akamaro mukuzamura ubukana bwindwara, kugabanya ibyago byo kwandura no kugabanya ibimenyetso nibimenyetso kubarwayi bafite imyaka 2 nayirenga. Igabanya uburibwe bwaho mu ruhu kandi ikarinda kurushaho kwiyongera kwindwara hamwe numwirondoro mwiza wumutekano. Imiterere yacyo irimo aboronatom, yoroshya uruhu rwinjira no guhuza hagati ya bimetal ya fosiforiesterase 4 enzyme. Kuri ubu irimo gutezwa imbere nkubuvuzi bwibanze bwa psoriasis.
Crisaborole ni Phosphodiesterase 4 Inhibitor. Uburyo bwibikorwa bya crisaborole ni nka Phosphodiesterase 4 Inhibitor.





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