Relugolix ikoreshwa mu kuvura kanseri ya prostate ku bagabo.
Amazina y'ibirango: Orgovyx
Icyiciro cyibiyobyabwenge: Antineoplastique - LHRH (GnRH) Antagonist Pitoito Suppressants
Kuboneka: Ibisabwa
Inda: Baza muganga wawe. Iyi miti irashobora kugirira nabi umwana uri mu nda.
Konsa: Baza muganga mbere yo gukoresha

Relugolix ni umunwa uboneka, udafite peptide gonadotropine-irekura imisemburo (GnRH cyangwa luteinizing hormone irekura imisemburo (LHRH)) antagonist, hamwe nibikorwa bya antineoplastique. Relugolix ihatanira guhuza no guhagarika reseptor ya GnRH muri glande y'imbere ya pitoito, ibyo byombi bikabuza GnRH guhuza reseptor ya GnRH kandi ikabuza gusohora no kurekura imisemburo ya luteinizing (LH) hamwe na hormone ikangura imisemburo (FSH). Ku bagabo, kubuza gusohora kwa LH birinda irekurwa rya testosterone muri selile ya Leydig mu bizamini. Kubera ko testosterone isabwa kugirango ikure rya prostate, kugabanya urugero rwa testosterone birashobora kubuza ikwirakwizwa rya kanseri ya prostate iterwa na hormone.

Relugolix ni imisemburo ya gonadotropine irekura imisemburo (GnRH) reseptor antagonist ikoreshwa mu kuvura indwara nyinshi zitanga imisemburo. Byemejwe bwa mbere mu Buyapani mu 2019, ku izina rya Relumina, kugira ngo bivure ibimenyetso bya fibroide nyababyeyi, ndetse vuba aha na FDA yo muri Amerika muri 2020, ku izina rya Orgovyx, kugira ngo bivure kanseri ya prostate yateye imbere. Relugolix nayo yize mu kuvura ibimenyetso bya endometriose. Relugolix niyambere (kandi kuri ubu gusa) ikoreshwa mu kanwa na GnRH reseptor antagonist yemerewe kuvura kanseri ya prostate - ubuvuzi busa nka [degarelix] busaba ubuyobozi bwimbuto - bityo rero butanga uburyo bworoshye bwo kuvura abarwayi bashobora gusaba gusurwa kwa muganga. kubuyobozi ninzobere mubuzima. Usibye kuba byoroshye gukoresha-gukoresha, relugolix yerekanwe ko isumba iyindi yo kwiheba kwa testosterone ugereranije na [leuprolide], ubundi buryo bwo kuvura androgène yabuze ikoreshwa mu kuvura kanseri ya prostate.

Relugolix ni Gonadotropine Irekura Hormone Receptor Antagonist. Uburyo bwibikorwa bya relugolix ni nka Gonadotropine Irekura Hormone Receptor Antagonist, na Cytochrome P450 3A Inducer, na Cytochrome P450 2B6 Inducer, hamwe na Inhibitor ya P-Glycoprotein. Ingaruka ya physiologic ya relugolix nuburyo bwo Kugabanuka kwa GnRH.

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