Uyu muti ukoreshwa nabagore kugirango bafashe kugabanya ububabare buciriritse cyangwa bukabije bitewe nindwara yitwa endometriose.
Gicurasi ishobora kuvura: Endometriose
Amazina y'ibirango: Orilissa
Icyiciro cyibiyobyabwenge: LHRH (GnRH) Antagonistes
Kuboneka: Ibisabwa
Inda: Irinde gukoresha mugihe utwite
Konsa: Baza muganga mbere yo gukoresha

Elagolix ni bioavailable yo mu kanwa, igisekuru cya kabiri, idafite peptide ishingiye, molekile ntoya hamwe na hormone irekura imisemburo ya gonadotropine (GnRH; LHRH) reseptor antagonist, hamwe nibikorwa byo guhagarika imisemburo.Ku buyobozi bwo mu kanwa, elagolix irushanwa na GnRH kugirango ihuze reseptor kandi ikabuza reseptor ya GnRH yerekana muri glande y'imbere.Ibi birinda gusohora imisemburo ya luteinizing (LH) hamwe na hormone itera imisemburo (FSH).Ku bagabo, kubuza gusohora kwa LH birinda irekurwa rya testosterone.Ku bagore, kubuza FSH na LH birinda umusaruro wa estrogene na ovaries.Kubuza ibimenyetso bya GnRH birashobora kuvura cyangwa gukumira ibimenyetso byindwara ziterwa na hormone.

Elagolix ni umunwa, nonaderoidal gonadotropine irekura imisemburo (GnRH) igabanya umusaruro wa estrogene kandi ikoreshwa mu kuvura ububabare bwa endometriose ku bagore.Ubuvuzi bwa Elagolix bujyanye nigipimo gito cyo hejuru ya serumu enzyme mugihe cyo kuvura kandi ntikirahuzwa nigihe cyo gukomeretsa umwijima bigaragara.

Elagolix yakoreshejwe mu bigeragezo yiga siyanse y'ibanze no kuvura Endometriose, Folliculogenezesi, Fibroide ya Uterine, Amaraso akomeye ya Uterine, no kuva amaraso akomeye.Guhera ku ya 24 Nyakanga 2018, ariko, Ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge (FDA) cyemeje elagolix ya AbbVie ku izina rya Orilissa nk’imisemburo ya mbere kandi yonyine yo mu kanwa ya gonadotropine isohora imisemburo (GnRH) yakorewe cyane cyane ku bagore bafite ububabare bukabije bwa endometriose.Byemejwe ko endometriose ari imwe mu ndwara z’abagore bakunze kugaragara muri Amerika.By'umwihariko, ibigereranyo byerekana ko umwe mu bagore icumi bafite imyaka yo kubyara yibasirwa na endometriose kandi akagira ibimenyetso byububabare.Byongeye kandi, abagore banduye iyi ndwara barashobora kubabazwa kugeza kumyaka itandatu kugeza ku icumi kandi bagasura abaganga benshi mbere yo kwisuzumisha neza.Icyakurikiyeho, nkuko Orilissa (elagolix) yemejwe na FDA mu isuzuma ryibanze, iki cyemezo gishya cyihuse giha inzobere mu buvuzi ubundi buryo bwingenzi bwo kuvura ibikenewe by’abagore batewe na endometriose, bitewe n'ubwoko bwabo n'uburemere bw'ububabare bwa endometriose. .

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